Get to Know Cannabigerol (CBG)
Cannabigerol (CBG) may not be as widely recognized as THC and CBD, but this cannabinoid also shows great promise with an array of potential uses.
What is Cannabigerol and how is it different?
Cannabigerol is a parent molecule to other cannabinoids. It is present in the young plant and then naturally synthesizes to create other cannabinoids as it matures. Through this process, about 1% of CBG is present in the mature plant, making it harder to produce and extract.
CBD and CBG have benefits without a psychoactive element, making it ideal for those who seek relief but not a “high”. It also interacts with both the CB1 and CB2 receptors. Through these receptors, CBG can connect with both the central and peripheral nervous systems. This differs from CBD that interacts with only the CB2 receptor.
What are the benefits of CBG?
The limited amounts of CBG have made it difficult for researchers to learn more about this cannabinoid. As demand grows, farmers and scientists work to improve techniques that give more CBG. The available research shows that this compound has great promise.
The following potential uses are an intriguing option for those who wish to treat their conditions with natural products.
- Antibacterial properties: a study published in March 2020 by the American Chemical Society, found that CBG has the potential to treat MRSA (an antibiotic resistant bacterial infection). This study also showed that CBG can penetrate the bacteria’s membrane and cure infection. As such, CBG has the potential to be therapeutic in a broad range of uses.
- Reduce Inflammation: the use of CBD and CBG for inflammation is common amongst its users. In an animal model of (IBD), CBG exhibited a reduction in the markers and symptoms of colitis. Although further research is needed, the 2013 study suggests that CBG may improve inflammation all over.
- Improve Glaucoma: many people are aware that THC is used to improve glaucoma. But, in a study comparing CBG and THC, both compounds produced a modest reduction in eye pressure and increased eye moisture. As such, both cannabinoids show potential as a treatment for glaucoma. It is worth noting that THC affected brain activity but CBG did not have this side effect.
- Slow Tumor Growth: a study published in Carcinogenesis discussed the potential of CBG to slow cell growth in colon cancer. This was also shown in a study published by The Journal of Pharmacology and Experimental Therapeutics in 2006 with breast cancer. These studies suggest further studies on CBG for the treatment and prevention of cancers.
- Neurodegenerative Protectant: in a 2015 experimental model of Huntington’s Disease, CBG acted as a neuroprotectant. It improved motor function and protected striatal neurons. The study also found that CBG gave a modest recovery after decreased motor performance as well as improved gene function. These results suggest that CBG may protect and improve neurological function.
Researching cannabinoids was difficult up until the passing of the 2018 Farm Bill. This bill made cannabinoids from the hemp plant federally legal in the United States. With every new study, we will better understand the diverse benefits of cannabinoids.
The current studies of CBG make it obvious that this cannabinoid is naturally powerful and worth pursuing further. For best results, find a high-quality broad-spectrum or full-spectrum CBD oil. Full-spectrum oils can contain both cannabinoids and allow them to team up.
Author: Bailee Morgan
Links: Antibacterial study:https://pubs.acs.org/doi/full/10.1021/acsinfecdis.9b00419
Colon cancer study:https://academic.oup.com/carcin/article/35/12/2787/335166
Breast Cancer study:https://jpet.aspetjournals.org/content/318/3/1375
2015 Huntington’s Disease study:https://link.springer.com/article/10.1007/s13311-014-0304-z#citeas